/Student project: Human tissue analysis using Raman Spectroscopy

Student project: Human tissue analysis using Raman Spectroscopy

Research & development - Wageningen | More than two weeks ago

This project aims to assess the feasibility of Raman spectroscopy to characterize adipose tissue.

Student project: Human tissue analysis using Raman Spectroscopy

What you will do

What if we were able to diagnose patients at an early stage and with completely non-invasive methods? Early diagnosis makes treatment more effective and may prevent or delay disease progression. At the OnePlanet Research Center we believe that applications of Raman spectroscopy in healthcare have the potential to revolutionize patient diagnostics, since measurements could be done completely non-invasively.

Raman spectroscopy is a remarkable technique which can measure chemical compositions in samples both non-destructively and at a distance. It works through an inelastic scattering process; when incident light (usually a laser) excites molecules in a tissue, these molecules will reflect light in a different wavelength. The reflected light’s wavelength is characteristic for the measured sample and can be used to differentiate different chemical structures with high sensitivity.

In this project, we want to study the feasibility of using Raman Spectroscopy to characterize adipose tissue of humans. This project consists of two parts. First, an experimental Raman set-up that is most suitable for the characterization of adipose tissue will be built and tested. This will be based on already existing systems and a thorough literature review. Experiments on different fat mixtures, data analysis strategy are part of the project.

Tasks:

  • Research the most suitable Raman set-up and make an experimental plan.
  • Build and test the experimental Raman set-up.
  • Show the feasibility of Raman Spectroscopy to discriminate different fat compositions using fat samples and phantoms.
  • Develop a data analysis strategy.

What we do for you

We offer a challenging and international environment at the forefront of technology. OnePlanet is a new collaboration of 3 renowned and globally respected research institutes/universities: Wageningen University & Research, Radboud University, Radboudumc, and imec. By joining the OnePlanet team, you will be part of a team of world changers, disruptive innovators, and practical thinkers. Here, your ideas will have an impact on our future lives.

Who you are

  • You are a Msc student in Physics, Optics, Chemistry, or similar field.
  • You are available for a (minimal) period of 6 months.
  • You have a strong interest in optical spectroscopy.
  • You have a strong interest in data analysis.
  • Knowledge of Raman Spectroscopy is a plus.
  • An interest in biomedical research is a plus.
  • Motivated student eager to expand knowledge in the field.
  • Good written and verbal English skills.
  • Entitled to do an internship in the Netherlands. This means that either you are either an EU/EEA citizen, or a non-EU/EEA citizen who is studying at a Dutch university and need to do an internship as part of your studies.

Interested

Click on ‘apply’ to submit your application. You will then be redirected to e-recruiting.

Please be advised that non-EU/EEA country students that are studying outside of the Netherlands, need to have a Dutch work-permit to be able to do an internship in the Netherlands. We do not facilitate this.